John Kulish, Personalized medicine, Hormone replacement therapy, Biodentical hormones, IV therapy, longevity medicine, Northville Michigan

Meet Dr. John Kulish

Dr. John Kulish is not your typical doctor. After decades of practicing as an Emergency Room (ER) physician, he saw firsthand the shortcomings of traditional healthcare, where the focus was often on treating illnesses and injuries reactively, rather than preventing them from happening in the first place. Inspired by his desire to make a lasting, positive impact on people’s lives, Dr. Kulish transitioned from the world of reactive medicine to the proactive, holistic approach that defines Best Life N of 1.

As the founder and medical director of Best Life N of 1, Dr. Kulish has built a wellness clinic focused on optimal health, longevity, and prevention, offering a personalized, data-driven approach to health that goes far beyond the traditional model of reactive care. Dr. Kulish’s vision is simple: Prevent health problems before they start and empower individuals to live their best, healthiest lives.

A Transformation in Healthcare Philosophy

Dr. Kulish’s career began in the fast-paced, high-pressure world of the emergency room, where every decision is made on the spot, often under extreme time constraints. The ER was a place where treating symptoms and saving lives took precedence over addressing the root causes of disease or focusing on long-term wellness. After many years of witnessing the cycle of chronic disease, preventable illnesses, and unnecessary hospitalizations, Dr. Kulish began to question the effectiveness of the reactive medical system.

He realized that while ER doctors are skilled in saving lives in acute situations, they were not equipped to offer solutions focused on wellness, prevention, and long-term health. Instead of waiting for health problems to manifest in the form of a heart attack, stroke, or debilitating disease, Dr. Kulish was determined to help people avoid these issues altogether by focusing on prevention and optimization.

This realization led him to pivot in his career, moving away from the traditional healthcare model to create Best Life N of 1, a clinic dedicated to providing personalized, proactive care that goes beyond simply fixing what’s broken. He envisioned a place where patients could receive individualized care based on advanced diagnostics and cutting-edge treatments—with a focus on empowerment, longevity, and wellness.

A Proactive Approach to Health and Wellness


At Best Life N of 1, Dr. Kulish’s approach centers on empowering patients to take control of their health before disease takes root—helping individuals thrive at every stage of life. Whether you’re looking to optimize physical performance, enhance mental clarity, or maximize longevity, Dr. Kulish and his team are committed to using the latest scientific advancements and personalized treatments to achieve your health goals.

Preventive medicine is about building a strong foundation for health and wellness before issues arise. By utilizing services such as DEXA scans, PNOE metabolic testing, IV therapy, Hormone Replacement Therapy, and more, Dr. Kulish tailors your treatment to your unique biology.

A Path to Optimal Wellness


Dr. Kulish’s ultimate goal is to offer people the ability to take a proactive approach to their health with the same level of care and attention that he provided in the emergency room, but in a preventative and wellness-focused context. This is why he created the Best Life N of 1 monthly membership—a comprehensive plan designed to optimize your health and maximize your longevity.

By subscribing to a monthly membership, you gain access to a range of personalized health services that are tailored specifically to you, including:

  • Comprehensive diagnostics through advanced testing and scans


  • Hormonal balance optimization with individualized plans


  • IV Vitamin Therapy for enhanced energy and immunity


  • Metabolic testing through PNOE to unlock your fitness potential


  • Exclusive access to recovery therapies like Sauna Therapy, Cold Plunge, and Hyperbaric Oxygen Therapy


  • Ongoing support from a team of dedicated experts to monitor your progress and adjust your plan as needed


Dr. Kulish’s proactive, data-driven approach ensures that you are always in control of your health. Instead of waiting for illness to disrupt your life, our monthly membership empowers you to stay ahead of potential health problems, providing the tools, knowledge, and resources you need to be your best self every day.